Research interests: protein crystallogenesis and crystallography
Facility responsibility: X-ray
ivanaks at seznam.cz (kuta at prf.jcu.cz)
(+420)-608-106-109
C 01 025
Part time also at the Institute of Microbiology ASCR, Nove Hrady
5 important publications:
Brezovsky J., Babkova P., Degtjarik O., Fortova A., Gora A., Iermak I., Rezacova P., Dvorak P., Kuta Smatanova I., Prokop Z., Chaloupkova R. and Damborsky J.: Engineering a de novo transport tunnel. ACS Catalysis 6, 7597-7610 (2016). DOI: 10.1021/acscatal.6b02081, IF 10,614
Liskova V., Bednar D., Prudnikova T., Rezacova P., Koudelakova T., Sebestova E., Kuta Smatanova I., Brezovsky J., Chaloupkova R., Damborsky J.: Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels. ChemCatChem 7, 648 –659 (2015). DOI: 10.1002/cctc.201402792, IF 4,803
Sykora J., Brezovsky J., Koudelakova T., Lahoda M., Fortova A., Chernovets T., Chaloupkova R., Stepankova V., Prokop Z., Kuta Smatanova I., Hof M., Damborsky J.: Dynamics and hydration explain failed functional transformation in dehalogenase design. Nature Chemical Biology, Vol. 10, No. 6, s. 428-430 (2014). ISSN 1552-4450. DOI:10.1038/nchembio.1502, IF 15,066
Koudelakova, T., Chaloupkova, R., Brezovsky, J., Prokop, Z., Sebestova, E., Hesseler, M., Khabiri, M., Plevaka, M., Kulik, D., Kuta Smatanova, I., Rezacova, P., Ettrich, R., Bornscheuer, U. T., Damborsky, J.: Engineering Enzyme Stability and Resistance to Organic Co-solvent by Access
Tunnel Modification. Angewandte Chemie International Edition 52, 1959-1963 (2013). DOI: 10.1002/anie.201206708, IF 11,994
Lapkouski M., Panjikar S., Janscak P., Kuta Smatanova I., Carey J., Ettrich R., Csefalvay E.: Structure of the motor subunit and translocation model for EcoR124I restriction-modification complex. Nature Structural & Molecular Biology 16(1), 94-5 (2009). Epub 2008 Dec 14. DOI: 10.1038/nsmb.1523, IF 12,595